iPTMnet Report for Q8IXZ2 (ZC3H3)
Protein Information
UniProt AC / UniProt ID | Q8IXZ2 / ZC3H3_HUMAN |
Protein Name | Zinc finger CCCH domain-containing protein 3 |
Gene Name | Name: ZC3H3 Synonyms:KIAA0150,SMICL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IXZ2 |
PRO Name | zinc finger CCCH domain-containing protein 3 (human) |
Definition | A zinc finger CCCH domain-containing protein 3 that is encoded in the genome of human. |
Short Label | hZC3H3 |
Category | organism-gene |
Q8IXZ2 (ZC3H3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R60 | Methylation | score1 | PhosphoSitePlus | |||
S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
C301 | Methylation | score1 | IEDB | 31844290 | ||
T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983 | ||
S414 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
K428 | Ubiquitination | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
S452 | Phosphorylation | score1 | PhosphoSitePlus | |||
S453 | Phosphorylation | score1 | PhosphoSitePlus | |||
T454 | Phosphorylation | score1 | PhosphoSitePlus | |||
K460 | Acetylation | score1 | PhosphoSitePlus | |||
S475 | Phosphorylation | score1 | PhosphoSitePlus | |||
K519 | Ubiquitination | score1 | PhosphoSitePlus | |||
K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
S552 | Phosphorylation | score1 | PhosphoSitePlus | |||
S571 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
S584 | Phosphorylation | score1 | PhosphoSitePlus | |||
S593 | Phosphorylation | score1 | PhosphoSitePlus | |||
S617 | Phosphorylation | score1 | PhosphoSitePlus | |||
T707 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
K723 | Ubiquitination | score1 | PhosphoSitePlus | |||
T775 | Phosphorylation | score1 | PhosphoSitePlus | |||
S810 | Phosphorylation | score1 | PhosphoSitePlus | |||
R821 | Methylation | score1 | PhosphoSitePlus | |||
S864 | Phosphorylation | score1 | PhosphoSitePlus | |||
S875 | Phosphorylation | score1 | PhosphoSitePlus | |||
S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
S877 | Phosphorylation | score1 | PhosphoSitePlus | |||
S878 | Phosphorylation | score1 | PhosphoSitePlus | |||
S917 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S918 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S920 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
K940 | Ubiquitination | score1 | PhosphoSitePlus | |||
K945 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S207 | Phosphorylation | score0 | HPRD | 17924679 | ||
S211 | Phosphorylation | score0 | HPRD | 20068231, 17924679 | ||
T303 | Phosphorylation | score0 | HPRD | 18491316 | ||
S383 | Phosphorylation | score0 | HPRD | 19007248 | ||
S408 | Phosphorylation | score0 | HPRD | 19651622 | ||
S412 | Phosphorylation | score0 | HPRD | 17081983 | ||
S414 | Phosphorylation | score0 | HPRD | 19651622 | ||
S569 | Phosphorylation | score0 | HPRD | 19007248 | ||
S571 | Phosphorylation | score0 | HPRD | 18691976, 19007248 | ||
S917 | Phosphorylation | score0 | HPRD | 18669648 | ||
S918 | Phosphorylation | score0 | HPRD | 18669648 | ||
S920 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S63 | F63 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S174 | L174 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] | |
S414 | F414 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S437 | L437 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
S452 | G452 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K519 | N519 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K534 | R534 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S918 | L918 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |