iPTMnet Report for Q8IXS8 (HYCC2)
Protein Information
UniProt AC / UniProt ID | Q8IXS8 / HYCC2_HUMAN |
Protein Name | Hyccin 2 |
Gene Name | Name: HYCC2 Synonyms:FAM126B; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IXS8 |
PRO Name | hyccin 2 (human) |
Definition | A hyccin 2 that is encoded in the genome of human. |
Short Label | hFAM126B |
Category | organism-gene |
Q8IXS8 (HYCC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T30 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y42 | Phosphorylation | score1 | PhosphoSitePlus | |||
S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y136 | Phosphorylation | score1 | PhosphoSitePlus | |||
K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
T306 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163 | ||
T308 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 15302935 | ||
S313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T319 | Phosphorylation | score1 | PhosphoSitePlus | |||
S321 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y408 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S419 | Phosphorylation | score1 | PhosphoSitePlus | |||
T423 | Phosphorylation | score1 | PhosphoSitePlus | |||
S430 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S442 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S444 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S456 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y487 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
T489 | Phosphorylation | score1 | PhosphoSitePlus | |||
S491 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R496 | Methylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
S521 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y42 | C42 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S367 | T367 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S402 | L402 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S456 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y487 | * | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
T489 | I489 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
R496 | W496 | Biomuta | DOID:1319 / brain cancer [ icgc ] |