iPTMnet Report for Q8IXK0 (PHC2)
Protein Information
UniProt AC / UniProt ID | Q8IXK0 / PHC2_HUMAN |
Protein Name | Polyhomeotic-like protein 2 |
Gene Name | Name: PHC2 Synonyms:EDR2,PH2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IXK0 |
PRO Name | polyhomeotic-like protein 2 (human) |
Definition | A polyhomeotic-like protein 2 that is encoded in the genome of human. |
Short Label | hPHC2 |
Category | organism-gene |
Q8IXK0 (PHC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
S591 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
Y601 | Phosphorylation | score1 | PhosphoSitePlus | |||
T616 | Phosphorylation | score1 | PhosphoSitePlus | |||
T617 | Phosphorylation | score1 | PhosphoSitePlus | |||
T618 | Phosphorylation | score1 | PhosphoSitePlus | |||
T619 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S621 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
K632 | Ubiquitination | score1 | PhosphoSitePlus | |||
K641 | Sumoylation | score1 | PhosphoSitePlus | |||
K655 | Ubiquitination | score1 | PhosphoSitePlus | |||
K667 | Acetylation | score1 | PhosphoSitePlus | |||
K667 | Ubiquitination | score1 | PhosphoSitePlus | |||
K675 | Acetylation | score1 | PhosphoSitePlus | |||
S682 | Phosphorylation | score1 | PhosphoSitePlus | |||
S701 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
S704 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
S733 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
C740 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S745 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
S751 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K793 | Ubiquitination | score1 | PhosphoSitePlus | |||
K841 | Sumoylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S591 | Phosphorylation | score0 | HPRD | 18669648, 19691289 | ||
T619 | Phosphorylation | score0 | HPRD | 18669648 | ||
S701 | Phosphorylation | score0 | HPRD | 17287340 | ||
S704 | Phosphorylation | score0 | HPRD | 17287340, 20068231 | ||
T709 | Phosphorylation | score0 | HPRD | 20068231 | ||
S733 | Phosphorylation | score0 | HPRD | 17525332 | ||
S745 | Phosphorylation | score0 | HPRD | 15302935 | ||
S751 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S56 | Phosphorylation | score0 | HPRD | 18669648, 19691289 | ||
T84 | Phosphorylation | score0 | HPRD | 18669648 | ||
S166 | Phosphorylation | score0 | HPRD | 17287340 | ||
S169 | Phosphorylation | score0 | HPRD | 17287340, 20068231 | ||
T174 | Phosphorylation | score0 | HPRD | 20068231 | ||
S198 | Phosphorylation | score0 | HPRD | 17525332 | ||
S210 | Phosphorylation | score0 | HPRD | 15302935 | ||
S216 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S621 | L621 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K710 | N710 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |