iPTMnet Report for Q8IWX8 (CHERP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWX8 / CHERP_HUMAN
Protein Name Calcium homeostasis endoplasmic reticulum protein
Gene Name Name: CHERP
Synonyms:DAN26;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWX8
DAG View
PRO Name calcium homeostasis endoplasmic reticulum protein (human)
Definition A calcium homeostasis endoplasmic reticulum protein that is encoded in the genome of human.
Short Label hCHERP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWX8 (CHERP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
K18 Acetylation PhosphoSitePlus   UniProt 19608861
K18 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
C190 Methylation IEDB 31844290
K239 Acetylation PhosphoSitePlus
R510 Methylation PhosphoSitePlus
R546 Methylation PhosphoSitePlus
R675 Methylation PhosphoSitePlus
S683 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y694 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
Y714 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
Y805 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S806 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
R811 Methylation PhosphoSitePlus
S813 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19651622, 18669648, 20068231
S815 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18452278, 19651622, 18669648, 19690332, 20068231
S817 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18452278, 19651622, 18669648, 19690332, 20068231
T819 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18452278, 19651622, 18669648, 20068231
S822 O-Glycosylation GlyGen 32119511, 33214551, 28510447, ...34019948, 34846842
S822 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17081983, 19651622, ...18669648, 20068231
S823 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
S828 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S830 O-Glycosylation GlyGen 32119511, 33214551, 28510447, ...34019948, 34846842
S830 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S837 Phosphorylation HPRD 17081983, 20068231
R838 Methylation PhosphoSitePlus
K844 Sumoylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus   UniProt 23186163
S857 Phosphorylation PhosphoSitePlus   UniProt 23186163
K879 Acetylation PhosphoSitePlus   UniProt 19608861
K879 Ubiquitination PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
K884 Ubiquitination PhosphoSitePlus
Y894 Phosphorylation PhosphoSitePlus
Y897 Phosphorylation PhosphoSitePlus
K901 Acetylation PhosphoSitePlus
K901 Methylation PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
Y903 Phosphorylation PhosphoSitePlus
S904 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 27920218, 18669648, 18212344
R908 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C190 Y190 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R675 C675 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S683 N683 Biomuta [ cosmic ]
S705 N705 Biomuta DOID:4159 / skin cancer [ cosmic ]
S755 L755 Biomuta DOID:1324 / lung cancer [ cosmic ]
S767 L767 Biomuta DOID:1612 / breast cancer [ icgc ]
S775 Y775 Biomuta DOID:3571 / liver cancer [ cosmic ]
S798 L798 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S798 P798 Biomuta DOID:363 / uterine cancer [ icgc ]
S800 Y800 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S804 L804 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S806 Y806 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R811 H811 Biomuta DOID:4362 / cervical cancer [ icgc ]
S815 F815 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S817 T817 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T819 P819 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
S823 F823 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S828 F828 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S830 L830 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R838 K838 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S855 R855 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K901 N901 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R908 S908 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R908 P908 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R908 H908 Biomuta DOID:363 / uterine cancer [ icgc ]