iPTMnet Report for Q8IWU6 (SULF1)
Protein Information
UniProt AC / UniProt ID | Q8IWU6 / SULF1_HUMAN |
Protein Name | Extracellular sulfatase Sulf-1 precursor |
Gene Name | Name: SULF1 Synonyms:KIAA1077; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IWU6 |
PRO Name | extracellular sulfatase Sulf-1 (human) |
Definition | An extracellular sulfatase Sulf-1 that is encoded in the genome of human. |
Short Label | hSULF1 |
Category | organism-gene |
Q8IWU6 (SULF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T24 | Phosphorylation | score1 | PhosphoSitePlus | |||
T76 | Phosphorylation | score1 | PhosphoSitePlus | |||
T83 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
T96 | Phosphorylation | score1 | PhosphoSitePlus | |||
N111 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
N131 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
N170 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
N197 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score1 | PhosphoSitePlus | |||
T367 | Phosphorylation | score1 | PhosphoSitePlus | |||
K417 | Acetylation | score1 | PhosphoSitePlus | |||
Y438 | Phosphorylation | score1 | PhosphoSitePlus | |||
N623 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
K648 | Ubiquitination | score1 | PhosphoSitePlus | |||
K656 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T285 | N285 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T367 | K367 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
T367 | M367 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y438 | S438 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |