iPTMnet Report for Q8IWE2 (FAM114A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWE2 / NXP20_HUMAN
Protein Name Protein NOXP20
Gene Name Name: FAM114A1
Synonyms:NOXP20;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWE2
DAG View
PRO Name protein NOXP20 (human)
Definition A protein NOXP20 that is encoded in the genome of human.
Short Label hFAM114A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWE2 (FAM114A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus   UniProt 20068231
S123 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K135 Methylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus   UniProt 24275569
T189 Phosphorylation PhosphoSitePlus   UniProt 24275569
S196 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T199 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S200 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S202 Phosphorylation PhosphoSitePlus   UniProt 24275569
S210 Phosphorylation PhosphoSitePlus
T238 O-Glycosylation GlyGen 23301498, 30379171, 36580660
S245 O-Glycosylation GlyGen 23301498, 30379171, 36580660
S245 Phosphorylation PhosphoSitePlus
K250 Acetylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus   UniProt 24275569
S263 Phosphorylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
T505 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S123 N123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S202 L202 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T238 N238 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K361 N361 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]
T437 N437 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T505 M505 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]