iPTMnet Report for Q8IW52 (SLITRK4)
Protein Information
UniProt AC / UniProt ID | Q8IW52 / SLIK4_HUMAN |
Protein Name | SLIT and NTRK-like protein 4 precursor |
Gene Name | Name: SLITRK4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IW52 |
PRO Name | SLIT and NTRK-like protein 4 (human) |
Definition | A SLIT and NTRK-like protein 4 that is encoded in the genome of human. |
Short Label | hSLITRK4 |
Category | organism-gene |
Q8IW52 (SLITRK4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T301 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T306 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T307 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T334 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K381 | Acetylation | score1 | PhosphoSitePlus | |||
S663 | Phosphorylation | score1 | PhosphoSitePlus | |||
T736 | Phosphorylation | score1 | PhosphoSitePlus | |||
S741 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622 | ||
T742 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622 | ||
S755 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y769 | Phosphorylation | score1 | PhosphoSitePlus | |||
K792 | Methylation | score1 | PhosphoSitePlus | |||
K801 | Methylation | score1 | PhosphoSitePlus | |||
Y811 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y824 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T307 | A307 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
T307 | K307 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K381 | E381 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K381 | N381 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S663 | Y663 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T736 | I736 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T736 | N736 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
S741 | I741 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S755 | C755 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K801 | N801 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y824 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |