iPTMnet Report for Q8IVV2 (LOXHD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IVV2 / LOXH1_HUMAN
Protein Name Lipoxygenase homology domain-containing protein 1
Gene Name Name: LOXHD1
Organism Homo sapiens (Human)

PRO ID PR:Q8IVV2
DAG View
PRO Name lipoxygenase homology domain-containing protein 1 (human)
Definition A lipoxygenase homology domain-containing protein 1 that is encoded in the genome of human.
Short Label hLOXHD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IVV2 (LOXHD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T301 Phosphorylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
Y686 Phosphorylation PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
T700 Phosphorylation PhosphoSitePlus
Y709 Phosphorylation PhosphoSitePlus
Y816 Phosphorylation PhosphoSitePlus
T830 Phosphorylation PhosphoSitePlus
T881 Phosphorylation PhosphoSitePlus
T992 Phosphorylation PhosphoSitePlus
T1000 Phosphorylation PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus
Y1227 Phosphorylation PhosphoSitePlus
Y1289 Phosphorylation PhosphoSitePlus
Y1554 Phosphorylation PhosphoSitePlus
T1568 Phosphorylation PhosphoSitePlus
S1570 Phosphorylation PhosphoSitePlus
T1602 Phosphorylation PhosphoSitePlus
K1716 Acetylation PhosphoSitePlus
T2042 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T301 S301 Biomuta DOID:1324 / lung cancer [ cosmic ]
S696 Y696 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S699 I699 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S699 R699 Biomuta DOID:1324 / lung cancer [ icgc ]
T700 K700 Biomuta DOID:3571 / liver cancer [ cosmic ]