iPTMnet Report for Q8IVT2 (MISP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IVT2 / MISP_HUMAN
Protein Name Mitotic interactor and substrate of PLK1
Gene Name Name: MISP
Synonyms:C19orf21;
Organism Homo sapiens (Human)

PRO ID PR:Q8IVT2
DAG View
PRO Name mitotic interactor and substrate of PLK1 (human)
Definition A mitotic interactor and substrate of PLK1 that is encoded in the genome of human.
Short Label hMISP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IVT2 (MISP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
T74 Phosphorylation PhosphoSitePlus
S78 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 23509069, 19691289, ...16565220, 19007248, 20068231
S84 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S155 Phosphorylation HPRD   PhosphoSitePlus 17081983
S156 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
T157 Phosphorylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
T164 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 23509069, 18220336, ...19691289, 18669648, 20068231
T172 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 23509069
S178 O-Glycosylation GlyGen 30379171, 33465208, 35083852, ...30059200, 35254053
S178 Phosphorylation HPRD   PhosphoSitePlus 19691289, 20068231
T179 Phosphorylation PhosphoSitePlus   UniProt 23186163
S202 Phosphorylation HPRD   PhosphoSitePlus 18212344
K208 Ubiquitination PhosphoSitePlus
S213 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648, 20068231
S214 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23509069, 20068231
T219 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19007248, 20068231, ...19691289
T224 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 23509069, 19007248, ...18669648, 20068231, 17924679
S228 O-Glycosylation GlyGen 30379171, 33465208, 35083852, ...30059200, 35254053
S228 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S278 Phosphorylation HPRD   phospho.ELM 18669648, 20068231
S281 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S284 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23509069, 19007248, ...18452278, 19651622, 18669648, 16565220, 20068231
T287 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23509069, 19007248, ...16565220, 19651622, 18669648, 18452278, 20068231
T291 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S335 Phosphorylation PhosphoSitePlus
T338 Phosphorylation HPRD   PhosphoSitePlus 20068231
S348 Phosphorylation Q96GD4 (AURKB) HPRD   PhosphoSitePlus   UniProt 22267324, 23186163, 18212344
Y350 Phosphorylation PhosphoSitePlus
S376 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
T377 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 17081983, 23509069, ...20058876, 19691289, 18669648, 20068231
S382 Phosphorylation UniProt 23509069
S394 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 17081983, 18491316, ...23186163, 18212344, 23509069, 18767875, 20058876, 19007248, 18452278, 19651622, 18669648, 16083285, 16565220, 19415658, 20068231, 19691289
S395 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 23509069, ...20058876, 19007248, 18452278, 19651622, 18669648, 19415658, 20068231, 19691289
S397 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...23509069, 19691289, 18452278, 18669648, 20068231
S400 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...19691289, 19007248, 19651622, 18669648, 19415658, 20068231
Y425 Phosphorylation HPRD 20068231
Y428 Phosphorylation HPRD   PhosphoSitePlus 20068231
S430 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 20068231
T433 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S439 Phosphorylation HPRD 20068231
S448 Phosphorylation HPRD 20068231
S449 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
T459 Phosphorylation HPRD   PhosphoSitePlus 20068231
T464 Phosphorylation HPRD   PhosphoSitePlus 20068231
S466 O-Glycosylation GlyGen 30379171, 33465208, 35083852, ...30059200, 35254053
S466 Phosphorylation HPRD   PhosphoSitePlus 20068231
S471 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...18767875, 19691289, 18452278, 17924679, 20068231, 18212344
S474 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983, 17924679
S479 Phosphorylation PhosphoSitePlus
R496 Methylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
S541 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18669648, 20068231, 18212344
S543 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 18212344, ...18767875, 19007248, 19691289, 18669648, 20068231
S544 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S553 Phosphorylation PhosphoSitePlus
S575 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...23509069, 19691289, 18452278, 18669648, 16565220, 20068231
T577 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19691289, 20068231
S582 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23509069, 20068231, ...18452278
S586 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23509069, 20068231, ...18452278
S608 Phosphorylation HPRD 19007248
K634 Ubiquitination PhosphoSitePlus
Y638 Phosphorylation PhosphoSitePlus
S675 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231, ...19007248