iPTMnet Report for Q8IVH2 (FOXP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IVH2 / FOXP4_HUMAN
Protein Name Forkhead box protein P4
Gene Name Name: FOXP4
Synonyms:FKHLA;
Organism Homo sapiens (Human)

PRO ID PR:Q8IVH2
DAG View
PRO Name forkhead box protein P4 (human)
Definition A forkhead box protein P4 that is encoded in the genome of human.
Short Label hFOXP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IVH2 (FOXP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation PhosphoSitePlus   UniProt 23186163
S57 Phosphorylation PhosphoSitePlus
S86 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S92 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K175 Sumoylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K232 Sumoylation PhosphoSitePlus
K246 Sumoylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
C309 Methylation IEDB 31844290
S360 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S390 O-Glycosylation GlyGen 32574038, 35132862, 35254053, ...34019948, 31492838, 35289036
S392 O-Glycosylation GlyGen 32574038, 35132862, 35254053, ...34019948, 31492838, 35289036
S394 O-Glycosylation GlyGen 32574038, 35132862, 35254053, ...34019948, 31492838, 35289036
S394 Phosphorylation PhosphoSitePlus
S429 O-Glycosylation GlyGen 32574038, 35132862, 35254053, ...34019948, 31492838, 35289036
S442 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
C447 Methylation IEDB 31844290
S448 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus   UniProt 23186163
T556 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation HPRD 18452278
S85 Phosphorylation HPRD 20068231
S86 Phosphorylation HPRD 19651622, 18669648, 20068231
S92 Phosphorylation HPRD 20068231
S394 Phosphorylation HPRD 19651622
T556 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation HPRD 18452278
S85 Phosphorylation HPRD 20068231
S86 Phosphorylation HPRD 19651622, 18669648, 20068231
S92 Phosphorylation HPRD 20068231
S392 Phosphorylation HPRD 19651622
T554 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation HPRD 18452278
S85 Phosphorylation HPRD 20068231
S86 Phosphorylation HPRD 19651622, 18669648, 20068231
S92 Phosphorylation HPRD 20068231
T543 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K169 E169 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K246 R246 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K246 M246 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S293 F293 Biomuta [ cosmic ]
T297 N297 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S442 N442 Biomuta DOID:363 / uterine cancer [ icgc ]
C447 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]