iPTMnet Report for Q8IV48 (ERI1)
Protein Information
UniProt AC / UniProt ID | Q8IV48 / ERI1_HUMAN |
Protein Name | 3'-5' exoribonuclease 1 |
Gene Name | Name: ERI1 Synonyms:3'EXO,THEX1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IV48 |
PRO Name | 3'-5' exoribonuclease 1 (human) |
Definition | A 3'-5' exoribonuclease 1 that is encoded in the genome of human. |
Short Label | hERI1 |
Category | organism-gene |
Q8IV48 (ERI1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
K49 | Sumoylation | score1 | PhosphoSitePlus | |||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
K52 | Sumoylation | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
S59 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S62 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
K67 | Acetylation | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K81 | Sumoylation | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Acetylation | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K49 | R49 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K87 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K92 | T92 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |