iPTMnet Report for Q8IV08 (PLD3)
Protein Information
UniProt AC / UniProt ID | Q8IV08 / PLD3_HUMAN |
Protein Name | 5'-3' exonuclease PLD3 |
Gene Name | Name: PLD3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IV08 |
PRO Name | 5'-3' exonuclease PLD3 (human) |
Definition | A 5'-3' exonuclease PLD3 that is encoded in the genome of human. |
Short Label | hPLD3 |
Category | organism-gene |
Q8IV08 (PLD3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y7 | Phosphorylation | score1 | PhosphoSitePlus | |||
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
N97 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
N132 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
N236 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
N284 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
N387 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K11 | N11 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K30 | R30 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
N97 | S97 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
N132 | S132 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S216 | N216 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
T225 | I225 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |