iPTMnet Report for Q8IUR5 (TMTC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUR5 / TMTC1_HUMAN
Protein Name Protein O-mannosyl-transferase TMTC1
Gene Name Name: TMTC1
ORFNames:ARG99;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUR5
DAG View
PRO Name protein O-mannosyl-transferase TMTC1 (human)
Definition A protein O-mannosyl-transferase TMTC1 that is encoded in the genome of human.
Short Label hTMTC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUR5 (TMTC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S244 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
Y414 Phosphorylation PhosphoSitePlus
Y420 Phosphorylation PhosphoSitePlus
T569 Phosphorylation PhosphoSitePlus
T696 Phosphorylation PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S244 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S244 L244 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y420 F420 Biomuta DOID:1324 / lung cancer [ cosmic ]
T569 A569 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T740 I740 Biomuta DOID:9256 / colorectal cancer [ cosmic ]