iPTMnet Report for Q8IUH8 (SPPL2C)
Protein Information
UniProt AC / UniProt ID | Q8IUH8 / SPP2C_HUMAN |
Protein Name | Signal peptide peptidase-like 2C precursor |
Gene Name | Name: SPPL2C Synonyms:IMP5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IUH8 |
PRO Name | signal peptide peptidase-like 2C (human) |
Definition | A signal peptide peptidase-like 2C that is encoded in the genome of human. |
Short Label | hSPPL2C |
Category | organism-gene |
Q8IUH8 (SPPL2C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
T93 | Phosphorylation | score1 | PhosphoSitePlus | |||
N100 | N-Glycosylation | score3 | GlyGen UniProt | 15385547 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | N17 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S85 | R85 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
N100 | S100 | Biomuta | [ cosmic ] |