Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YC3 / LRC33_HUMAN
Protein Name Transforming growth factor beta activator LRRC33 precursor
Gene Name Name: NRROS
Synonyms:LRRC33;ORFNames:UNQ3030/PRO9833;
Organism Homo sapiens (Human)

PRO ID PR:Q86YC3
DAG View
PRO Name transforming growth factor beta activator LRRC33 (human)
Definition A transforming growth factor beta activator LRRC33 that is encoded in the genome of human.
Short Label hNRROS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YC3 (NRROS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K35 Ubiquitination PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
N292 N-Glycosylation GlyGen 24190977
C547 Methylation IEDB 31844290
K576 Ubiquitination PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T145 M145 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S158 P158 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]