iPTMnet Report for Q86X29 (LSR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86X29 / LSR_HUMAN
Protein Name Lipolysis-stimulated lipoprotein receptor
Gene Name Name: LSR
Synonyms:ILDR3,LISCH;
Organism Homo sapiens (Human)

PRO ID PR:Q86X29
DAG View
PRO Name lipolysis-stimulated lipoprotein receptor (human)
Definition A lipolysis-stimulated lipoprotein receptor that is encoded in the genome of human.
Short Label hLSR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86X29 (LSR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation HPRD   PhosphoSitePlus 20068231
S23 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S141 O-Glycosylation GlyGen 30459171, 25813380
K179 Ubiquitination PhosphoSitePlus
T185 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T185 Phosphorylation IEDB   PhosphoSitePlus 27869121
Y189 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 19901323
K313 Ubiquitination PhosphoSitePlus
T316 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S317 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S321 O-Glycosylation GlyGen 25813380
S321 Phosphorylation PhosphoSitePlus
Y323 Phosphorylation HPRD   PhosphoSitePlus 19901323
S326 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S326 Phosphorylation HPRD   PhosphoSitePlus 19901323
T327 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T327 Phosphorylation PhosphoSitePlus
Y328 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 19901323
S332 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S332 Phosphorylation HPRD   PhosphoSitePlus 19901323
T336 O-Glycosylation GlyGen 25813380
T336 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
S363 O-Glycosylation GlyGen 25813380
S363 Phosphorylation PhosphoSitePlus
S364 Phosphorylation HPRD 20068231
S365 Phosphorylation PhosphoSitePlus   UniProt 23186163
S371 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S371 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y372 O-Glycosylation GlyGen 23584533, 25813380
Y372 Phosphorylation HPRD   PhosphoSitePlus 19901323
T379 O-Glycosylation GlyGen 25813380
T379 Phosphorylation PhosphoSitePlus
S381 O-Glycosylation GlyGen 25813380
S381 Phosphorylation PhosphoSitePlus
S382 O-Glycosylation GlyGen 25813380
S382 Phosphorylation PhosphoSitePlus
S385 O-Glycosylation GlyGen 25813380
S389 O-Glycosylation GlyGen 25813380
S389 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y391 Phosphorylation PhosphoSitePlus
S396 O-Glycosylation GlyGen 25813380
S396 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S401 O-Glycosylation GlyGen 25813380
S401 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 15316024, 19901323
Y407 Phosphorylation HPRD   PhosphoSitePlus 19901323
K410 Ubiquitination PhosphoSitePlus
S418 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S418 Phosphorylation PhosphoSitePlus
S424 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S424 Phosphorylation PhosphoSitePlus
S432 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S432 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T435 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S436 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S436 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S444 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S447 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T453 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T453 Phosphorylation PhosphoSitePlus   UniProt 23186163
S464 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S464 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 20068231, ...24275569
S467 O-Glycosylation GlyGen 25813380
S467 Phosphorylation PhosphoSitePlus   UniProt 23186163
S493 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 19664994, ...33936100, 18452278, 24275569, 20166139, 30784271
T501 O-Glycosylation GlyGen 25813380
T501 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19664994, 19651622, ...18669648, 24275569, 20166139
S504 O-Glycosylation GlyGen 25813380
S504 Phosphorylation PhosphoSitePlus
T505 O-Glycosylation GlyGen 25813380
T505 Phosphorylation PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
S510 O-Glycosylation GlyGen 25813380
S510 Phosphorylation PhosphoSitePlus
S512 O-Glycosylation GlyGen 25813380
S512 Phosphorylation PhosphoSitePlus
T514 O-Glycosylation GlyGen 25813380
T514 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S515 O-Glycosylation GlyGen 25813380
S515 Phosphorylation PhosphoSitePlus
Y523 O-Glycosylation GlyGen 25813380
Y523 Phosphorylation PhosphoSitePlus
S528 O-Glycosylation GlyGen 25813380
S528 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17693683
S530 O-Glycosylation GlyGen 25813380
S530 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 18318008, ...19651622, 24275569, 17693683, 20166139
Y535 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18083107, 19901323, 24275569
S540 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 20166139
S546 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S546 Phosphorylation PhosphoSitePlus
Y551 O-Glycosylation GlyGen 25813380
Y551 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 19901323, 17389395, ...17016520
S556 Phosphorylation PhosphoSitePlus
T571 O-Glycosylation GlyGen 25813380
S579 O-Glycosylation GlyGen 25813380
S579 Phosphorylation PhosphoSitePlus   UniProt 23186163
S581 Phosphorylation HPRD   PhosphoSitePlus 19664994
Y586 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 19901323, 17389395, ...17016520
Y615 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107, 19901323
Y616 Phosphorylation HPRD   PhosphoSitePlus 19901323
Y623 Phosphorylation HPRD   PhosphoSitePlus 19901323
S624 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18767875, 19664995, ...19651622, 19415658, 20068231
S631 Phosphorylation PhosphoSitePlus   UniProt 24275569
K638 Ubiquitination PhosphoSitePlus
S643 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 18767875, ...19664995, 19651622, 19415658, 20068231
S646 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 16083285, 23186163, ...19651622, 24275569, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S366 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S141 F141 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
Y190 C190 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S332 F332 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y352 H352 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S363 N363 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S396 G396 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y406 H406 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S444 F444 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S447 Y447 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S464 A464 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S493 Y493 Biomuta DOID:3571 / liver cancer [ cosmic ]
T505 I505 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T505 S505 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S510 G510 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y523 N523 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S546 A546 Biomuta DOID:1612 / breast cancer [ cosmic ]
S546 F546 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S556 F556 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S579 C579 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y623 D623 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S624 L624 Biomuta DOID:1324 / lung cancer [ cosmic ]
K638 Q638 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S646 N646 Biomuta DOID:10534 / stomach cancer [ cosmic ]