iPTMnet Report for Q86WA8 (LONP2)
Protein Information
UniProt AC / UniProt ID | Q86WA8 / LONP2_HUMAN |
Protein Name | Lon protease homolog 2, peroxisomal |
Gene Name | Name: LONP2 Synonyms:LONP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86WA8 |
PRO Name | Lon protease homolog 2, peroxisomal (human) |
Definition | A peroxisomal Lon protease 2 that is encoded in the genome of human. |
Short Label | hLONP2 |
Category | organism-gene |
Q86WA8 (LONP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
C106 | Methylation | score1 | IEDB | 31844290 | ||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
C137 | Methylation | score1 | IEDB | 31844290 | ||
C290 | Methylation | score1 | IEDB | 31844290 | ||
Y307 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y344 | Phosphorylation | score1 | PhosphoSitePlus | |||
M346 | Methylation | score2 | IEDB | 25418920 | ||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y356 | Phosphorylation | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
C372 | Methylation | score1 | IEDB | 31844290 | ||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
T416 | Phosphorylation | score1 | PhosphoSitePlus | |||
K446 | Ubiquitination | score1 | PhosphoSitePlus | |||
K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
S592 | Phosphorylation | score1 | PhosphoSitePlus | |||
K709 | Acetylation | score1 | PhosphoSitePlus | |||
Y711 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C137 | S137 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
C290 | R290 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y344 | C344 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
M346 | L346 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K348 | I348 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |