Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86W26 / NAL10_HUMAN
Protein Name NACHT, LRR and PYD domains-containing protein 10
Gene Name Name: NLRP10
Synonyms:NALP10,NOD8,PYNOD;
Organism Homo sapiens (Human)

PRO ID PR:Q86W26
DAG View
PRO Name NACHT, LRR and PYD domains-containing protein 10 (human)
Definition A NACHT, LRR and PYD domains-containing protein 10 that is encoded in the genome of human.
Short Label hNLRP10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86W26 (NLRP10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T36 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S268 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y323 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
T377 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
K605 Acetylation PhosphoSitePlus
S639 Phosphorylation HPRD   PhosphoSitePlus 20068231
T640 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T36 I36 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y323 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K332 M332 Biomuta DOID:1324 / lung cancer [ cosmic ]
S639 Y639 Biomuta DOID:9256 / colorectal cancer [ cosmic ]