iPTMnet Report for Q86VZ1 (P2RY8)
Protein Information
UniProt AC / UniProt ID | Q86VZ1 / P2RY8_HUMAN |
Protein Name | P2Y purinoceptor 8 |
Gene Name | Name: P2RY8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86VZ1 |
PRO Name | P2Y purinoceptor 8 (human) |
Definition | A P2Y purinoceptor 8 that is encoded in the genome of human. |
Short Label | hP2RY8 |
Category | organism-gene |
Q86VZ1 (P2RY8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N5 | N-Glycosylation | score2 | GlyGen UniProt | 19349973, 24190977 | ||
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
N11 | N-Glycosylation | score2 | GlyGen UniProt | 19349973, 24190977 | ||
T13 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18491316 | ||
Y127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
C212 | Methylation | score1 | IEDB | 31844290 | ||
S263 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
S327 | Phosphorylation | score1 | PhosphoSitePlus | |||
T331 | Phosphorylation | score1 | PhosphoSitePlus | |||
S332 | Phosphorylation | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S357 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T320 | S320 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T320 | M320 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S327 | F327 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S327 | C327 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S327 | Y327 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T331 | M331 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] | |
S332 | P332 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S335 | F335 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |