Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86VQ3 / TXND2_HUMAN
Protein Name Thioredoxin domain-containing protein 2
Gene Name Name: TXNDC2
Synonyms:SPTRX,SPTRX1;
Organism Homo sapiens (Human)

PRO ID PR:Q86VQ3
DAG View
PRO Name thioredoxin domain-containing protein 2 (human)
Definition A thioredoxin domain-containing protein 2 that is encoded in the genome of human.
Short Label hTXNDC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86VQ3 (TXNDC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S172 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K542 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T351 A351 Biomuta DOID:4159 / skin cancer [ cosmic ]
S407 F407 Biomuta DOID:4159 / skin cancer [ cosmic ]
K542 N542 Biomuta DOID:363 / uterine cancer [ icgc ]