iPTMnet Report for Q86UR5 (RIMS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UR5 / RIMS1_HUMAN
Protein Name Regulating synaptic membrane exocytosis protein 1
Gene Name Name: RIMS1
Synonyms:KIAA0340,RAB3IP2,RIM1;ORFNames:Nbla00761;
Organism Homo sapiens (Human)

PRO ID PR:Q86UR5
DAG View
PRO Name regulating synaptic membrane exocytosis protein 1 (human)
Definition A regulating synaptic membrane exocytosis protein 1 that is encoded in the genome of human.
Short Label hRIMS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UR5 (RIMS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T220 Phosphorylation PhosphoSitePlus
S242 Phosphorylation Q9UQM7 (CAMK2A) Signor 12871946
S288 Phosphorylation Q9UQM7 (CAMK2A) Signor 12871946
S324 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T398 O-Glycosylation GlyGen 30379171, 36240223, 28657654
T398 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K488 Sumoylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
T636 O-Glycosylation GlyGen 30379171, 36240223, 28657654
T636 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
Y781 Phosphorylation PhosphoSitePlus
Y785 Phosphorylation PhosphoSitePlus
S881 Phosphorylation PhosphoSitePlus
Y926 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1147 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation PhosphoSitePlus
T1179 O-Glycosylation GlyGen 30379171, 36240223, 28657654
T1179 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
S1252 Phosphorylation PhosphoSitePlus
T1254 Phosphorylation PhosphoSitePlus
S1256 Phosphorylation PhosphoSitePlus
T1261 Phosphorylation PhosphoSitePlus
S1331 Phosphorylation PhosphoSitePlus
S1336 Phosphorylation phospho.ELM 18669648
S1339 Phosphorylation PhosphoSitePlus
S1340 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1342 Phosphorylation phospho.ELM 18669648
S1345 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus
S1354 Phosphorylation PhosphoSitePlus
S1357 Phosphorylation PhosphoSitePlus
S1377 O-Glycosylation GlyGen 30379171, 36240223, 28657654
T1407 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1414 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1416 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1422 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1433 Phosphorylation PhosphoSitePlus
S1435 Phosphorylation PhosphoSitePlus
S1443 Phosphorylation PhosphoSitePlus
S1450 Phosphorylation PhosphoSitePlus
T1455 Phosphorylation PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus
K1463 Ubiquitination PhosphoSitePlus
S1486 Phosphorylation phospho.ELM 18669648
S1493 Phosphorylation phospho.ELM 18669648
S1562 Phosphorylation PhosphoSitePlus
T1564 Phosphorylation PhosphoSitePlus
Y1576 Phosphorylation PhosphoSitePlus
Y1580 Phosphorylation PhosphoSitePlus
S1613 Phosphorylation PhosphoSitePlus
Y1627 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T1668 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T1670 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1677 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S1679 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S1680 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S1683 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1684 Phosphorylation phospho.ELM 18669648
S1692 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
T636 Phosphorylation HPRD 20068231
S1336 Phosphorylation HPRD 18669648
S1340 Phosphorylation HPRD 18669648
S1342 Phosphorylation HPRD 18669648
T1407 Phosphorylation HPRD 18669648
S1414 Phosphorylation HPRD 18669648
S1416 Phosphorylation HPRD 18669648
T1422 Phosphorylation HPRD 18669648
S1486 Phosphorylation HPRD 18669648
S1493 Phosphorylation HPRD 18669648
S1562 Phosphorylation HPRD 19413330
T1564 Phosphorylation HPRD 19413330
S1677 Phosphorylation HPRD 18669648, 20068231
S1679 Phosphorylation HPRD 18669648
S1680 Phosphorylation HPRD 18669648, 20068231
S1683 Phosphorylation HPRD 18669648
S1684 Phosphorylation HPRD 18669648
S1692 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T560 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1129 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S500 Y500 Biomuta DOID:363 / uterine cancer [ icgc ]
S642 C642 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S881 L881 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y926 H926 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S967 T967 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S997 P997 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1065 N1065 Biomuta DOID:2998 / testicular cancer [ cosmic ]
S1076 L1076 Biomuta [ cosmic ]
T1254 I1254 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1256 C1256 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1331 R1331 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1377 G1377 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1414 N1414 Biomuta [ cosmic ]
S1414 G1414 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1433 I1433 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1457 L1457 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1493 N1493 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1562 N1562 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y1576 D1576 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1677 F1677 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1679 L1679 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1680 C1680 Biomuta DOID:1324 / lung cancer [ cosmic ]