iPTMnet Report for Q86UB9 (TMEM135)
Protein Information
UniProt AC / UniProt ID | Q86UB9 / TM135_HUMAN |
Protein Name | Transmembrane protein 135 |
Gene Name | Name: TMEM135 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86UB9 |
PRO Name | transmembrane protein 135 (human) |
Definition | A transmembrane protein 135 that is encoded in the genome of human. |
Short Label | hTMEM135 |
Category | organism-gene |
Q86UB9 (TMEM135) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C12 | Methylation | score1 | IEDB | 31844290 | ||
S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
S181 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
C250 | Methylation | score1 | IEDB | 31844290 | ||
Y344 | Phosphorylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
K433 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y128 | F128 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
Y128 | H128 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S181 | C181 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
Y344 | H344 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |