iPTMnet Report for Q86U70 (LDB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86U70 / LDB1_HUMAN
Protein Name LIM domain-binding protein 1
Gene Name Name: LDB1
Synonyms:CLIM2;
Organism Homo sapiens (Human)

PRO ID PR:Q86U70
DAG View
PRO Name LIM domain-binding protein 1 (human)
Definition A LIM domain-binding protein 1 that is encoded in the genome of human.
Short Label hLDB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86U70 (LDB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus   RLIMS-P 20570862
S19 Phosphorylation PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
C177 Methylation IEDB 31844290
K260 Ubiquitination PhosphoSitePlus
T261 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163
K271 Methylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
R280 Methylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K393 Acetylation PhosphoSitePlus
S402 O-Glycosylation GlyGen 30379171, 34019948, 30620550, ...35289036, 35254053
S402 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
S407 O-Glycosylation GlyGen 30379171, 34019948, 30620550, ...35289036, 35254053
S407 Phosphorylation PhosphoSitePlus
S410 O-Glycosylation GlyGen 30379171, 34019948, 30620550, ...35289036, 35254053
S410 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T25 Phosphorylation HPRD 19651622
K134 Ubiquitination PhosphoSitePlus
T225 Phosphorylation HPRD 19664994
Y226 Phosphorylation HPRD 19664994
S266 Phosphorylation HPRD 19413330, 19651622
T270 Phosphorylation HPRD 19413330
T291 Phosphorylation HPRD 18452278
K365 Ubiquitination PhosphoSitePlus
S374 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T25 S25 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y226 C226 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T270 I270 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S374 F374 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]