iPTMnet Report for Q86TC9 (MYPN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86TC9 / MYPN_HUMAN
Protein Name Myopalladin
Gene Name Name: MYPN
Synonyms:MYOP;
Organism Homo sapiens (Human)

PRO ID PR:Q86TC9
DAG View
PRO Name myopalladin (human)
Definition A myopalladin that is encoded in the genome of human.
Short Label hMYPN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86TC9 (MYPN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y85 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus   UniProt 20068231
S108 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K184 Acetylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
T250 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T251 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S254 Phosphorylation PhosphoSitePlus
S255 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S257 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S258 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y260 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y261 Phosphorylation phospho.ELM 18669648
T389 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
T390 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
S391 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
T412 Phosphorylation PhosphoSitePlus
S418 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T420 Phosphorylation phospho.ELM 18669648
S561 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
S643 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S644 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S684 Phosphorylation PhosphoSitePlus
S691 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
S697 Phosphorylation PhosphoSitePlus
T704 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
K711 Ubiquitination PhosphoSitePlus
S714 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
S715 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491, 29237092
S719 O-Glycosylation GlyGen 31373491
S719 Phosphorylation PhosphoSitePlus
T732 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
T733 O-Glycosylation GlyGen 33214551, 30379171, 31492838, ...30620550, 34019948, 36240223, 35254053, 31373491
T757 Phosphorylation PhosphoSitePlus
S759 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K760 Ubiquitination PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
R810 Methylation PhosphoSitePlus
S813 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
S818 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
S821 Phosphorylation phospho.ELM 18669648
R850 Methylation PhosphoSitePlus
S867 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K880 Ubiquitination PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus   UniProt 23186163
T923 Phosphorylation PhosphoSitePlus
S928 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
K941 Ubiquitination PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
R1053 Methylation PhosphoSitePlus
K1145 Ubiquitination PhosphoSitePlus
K1170 Ubiquitination PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
Y1284 Phosphorylation PhosphoSitePlus
T1288 O-Glycosylation GlyGen 31373491
Site PTM Type PTM Enzyme Score Source PMID
S101 Phosphorylation HPRD 17322306, 18691976, 20068231, ...18767875
S124 Phosphorylation HPRD 20068231
T250 Phosphorylation HPRD 18691976, 18669648, 20068231
T251 Phosphorylation HPRD 18669648, 19415658, 20068231
S254 Phosphorylation HPRD 20068231
S255 Phosphorylation HPRD 18691976, 18669648, 20068231
S257 Phosphorylation HPRD 18669648
S258 Phosphorylation HPRD 18669648
Y260 Phosphorylation HPRD 18669648
Y261 Phosphorylation HPRD 18669648
S385 Phosphorylation HPRD 20068231
S418 Phosphorylation HPRD 18691976, 18669648, 20068231
T420 Phosphorylation HPRD 18669648, 20068231
S561 Phosphorylation HPRD 20068231
S643 Phosphorylation HPRD 18669648, 18491316, 19691289
S644 Phosphorylation HPRD 17322306, 18669648, 18452278
S683 Phosphorylation HPRD 20068231
S759 Phosphorylation HPRD 18669648
S813 Phosphorylation HPRD 18669648, 16964243, 20068231
S818 Phosphorylation HPRD 18669648, 16964243, 20068231
S821 Phosphorylation HPRD 18669648
S867 Phosphorylation HPRD 18669648, 19691289, 20068231
S928 Phosphorylation HPRD 18691976, 18767875, 19691289, ...18452278, 17322306, 18669648, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S101 F101 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S101 Y101 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S108 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S131 R131 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S196 N196 Biomuta [ cosmic ]
S197 F197 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S198 N198 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T251 S251 Biomuta DOID:1324 / lung cancer [ cosmic ]
S257 L257 Biomuta DOID:4159 / skin cancer [ cosmic ]
S258 Y258 Biomuta DOID:363 / uterine cancer [ icgc ]
S385 P385 Biomuta DOID:1324 / lung cancer [ cosmic ]
S612 A612 Biomuta DOID:4159 / skin cancer [ cosmic ]
S643 Y643 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S643 C643 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S644 F644 Biomuta DOID:4159 / skin cancer [ cosmic ]
S691 N691 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S719 I719 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T732 I732 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T733 I733 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R810 S810 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R810 H810 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S818 C818 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S821 N821 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R850 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S907 R907 Biomuta DOID:363 / uterine cancer [ icgc ]
S960 F960 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1038 R1038 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S1047 F1047 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1170 N1170 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1170 I1170 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K1207 T1207 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1284 * Biomuta DOID:1324 / lung cancer [ cosmic ]