iPTMnet Report for Q7Z7E8 (UBE2Q1)
Protein Information
UniProt AC / UniProt ID | Q7Z7E8 / UB2Q1_HUMAN |
Protein Name | Ubiquitin-conjugating enzyme E2 Q1 |
Gene Name | Name: UBE2Q1 Synonyms:NICE5,UBE2Q;ORFNames:PRO3094; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z7E8 |
PRO Name | ubiquitin-conjugating enzyme E2 Q1 (human) |
Definition | A ubiquitin-conjugating enzyme E2 Q1 that is encoded in the genome of human. |
Short Label | hUBE2Q1 |
Category | organism-gene |
Q7Z7E8 (UBE2Q1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 22223895 | ||
K46 | Ubiquitination | score1 | PhosphoSitePlus | |||
S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Sumoylation | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
C157 | Methylation | score1 | IEDB | 31844290 | ||
S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K232 | Acetylation | score1 | PhosphoSitePlus | |||
K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Acetylation | score1 | PhosphoSitePlus | |||
Y241 | Phosphorylation | score1 | PhosphoSitePlus | |||
S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K307 | Ubiquitination | score1 | PhosphoSitePlus | |||
K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
K403 | Ubiquitination | score1 | PhosphoSitePlus | |||
S404 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y415 | Phosphorylation | score1 | PhosphoSitePlus | |||
T416 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C157 | W157 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
K232 | T232 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y241 | C241 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S247 | C247 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S401 | P401 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |