iPTMnet Report for Q7Z5J4 (RAI1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z5J4 / RAI1_HUMAN
Protein Name Retinoic acid-induced protein 1
Gene Name Name: RAI1
Synonyms:KIAA1820;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z5J4
DAG View
PRO Name retinoic acid-induced protein 1 (human)
Definition A retinoic acid-induced protein 1 that is encoded in the genome of human.
Short Label hRAI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z5J4 (RAI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K13 Methylation PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
R249 Methylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
T330 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 30379171, 32574038, 34019948, 35132862, 31492838, 35289036
Y334 Phosphorylation IEDB 35494241
S339 O-Glycosylation GlyGen 32574038
S339 Phosphorylation PhosphoSitePlus   UniProt 23186163
S341 O-Glycosylation GlyGen 32574038
S341 Phosphorylation PhosphoSitePlus
S343 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 32574038, 34019948, 35132862, 31492838, 35289036
S345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
K466 Ubiquitination PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y517 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S568 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S571 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S574 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K586 Ubiquitination PhosphoSitePlus
K621 Sumoylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K675 Ubiquitination PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
S683 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
S691 Phosphorylation PhosphoSitePlus
T696 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K700 Ubiquitination PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
K774 Acetylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S805 Phosphorylation PhosphoSitePlus   UniProt 23186163
K811 Sumoylation PhosphoSitePlus
K811 Ubiquitination PhosphoSitePlus
K819 Sumoylation PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
Y871 Phosphorylation PhosphoSitePlus
S872 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
S880 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S892 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K901 Sumoylation PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
K911 Ubiquitination PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
S1064 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T1068 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   UniProt 22028470, 19690332
T1077 Phosphorylation PhosphoSitePlus
K1083 Acetylation PhosphoSitePlus
K1087 Acetylation PhosphoSitePlus
K1093 Acetylation PhosphoSitePlus
K1096 Acetylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
S1107 Phosphorylation PhosphoSitePlus
S1108 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1110 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1119 Phosphorylation PhosphoSitePlus
S1121 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1122 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1126 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
T1136 Phosphorylation PhosphoSitePlus
K1139 Acetylation PhosphoSitePlus
T1152 Phosphorylation PhosphoSitePlus
S1158 Phosphorylation PhosphoSitePlus
S1164 Phosphorylation PhosphoSitePlus
S1181 Phosphorylation PhosphoSitePlus
K1188 Methylation PhosphoSitePlus
K1188 Sumoylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
K1223 Methylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1243 Phosphorylation PhosphoSitePlus
S1247 Phosphorylation PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
S1274 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
T1297 Phosphorylation PhosphoSitePlus
K1303 Methylation PhosphoSitePlus
K1303 Ubiquitination PhosphoSitePlus
K1328 Sumoylation PhosphoSitePlus
S1338 Phosphorylation PhosphoSitePlus
K1347 Methylation PhosphoSitePlus
S1352 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S1358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S1360 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1362 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1374 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
T1387 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus
K1411 Acetylation PhosphoSitePlus
S1419 Phosphorylation PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus
T1426 Phosphorylation PhosphoSitePlus
T1430 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1431 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1448 Phosphorylation PhosphoSitePlus
R1452 Methylation PhosphoSitePlus
T1476 Phosphorylation PhosphoSitePlus
S1581 Phosphorylation PhosphoSitePlus
S1588 Phosphorylation PhosphoSitePlus
S1590 Phosphorylation PhosphoSitePlus
T1592 Phosphorylation PhosphoSitePlus
S1596 Phosphorylation PhosphoSitePlus
T1608 Phosphorylation PhosphoSitePlus
T1609 Phosphorylation PhosphoSitePlus
T1612 Phosphorylation PhosphoSitePlus
S1616 Phosphorylation PhosphoSitePlus
S1733 Phosphorylation PhosphoSitePlus
S1772 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 32574038, 34019948, 35132862, 31492838, 35289036
S1772 Phosphorylation PhosphoSitePlus
S1777 Phosphorylation PhosphoSitePlus
S1782 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T149 Phosphorylation HPRD 20068231
S568 Phosphorylation HPRD 17081983, 20068231, 18452278
S571 Phosphorylation HPRD 17081983, 20068231
S574 Phosphorylation HPRD 17081983, 18452278
S683 Phosphorylation HPRD 18669648, 20068231
T696 Phosphorylation HPRD 18669648
S880 Phosphorylation HPRD 18669648
S892 Phosphorylation HPRD 18669648, 18452278
S924 Phosphorylation HPRD 20068231
S1107 Phosphorylation HPRD 19413330, 20068231
S1108 Phosphorylation HPRD 18669648
S1110 Phosphorylation HPRD 19413330, 18669648, 20068231
S1119 Phosphorylation HPRD 19413330
S1121 Phosphorylation HPRD 18669648, 20068231
S1122 Phosphorylation HPRD 18669648, 20068231
S1126 Phosphorylation HPRD 19413330
S1135 Phosphorylation HPRD 20068231
T1186 Phosphorylation HPRD 20068231
S1266 Phosphorylation HPRD 20068231
S1338 Phosphorylation HPRD 19413330, 20068231
S1352 Phosphorylation HPRD 19413330, 18669648, 19691289, ...20068231
S1358 Phosphorylation HPRD 19413330, 18669648, 20068231
S1360 Phosphorylation HPRD 18669648
S1362 Phosphorylation HPRD 18669648
S1374 Phosphorylation HPRD 19413330, 18669648, 19691289, ...20068231
T1430 Phosphorylation HPRD 18669648
S1431 Phosphorylation HPRD 18669648, 20068231
T1476 Phosphorylation HPRD 20068231, 17924679
S1616 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y30 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S58 I58 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S67 C67 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S271 L271 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K466 N466 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S519 N519 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S538 G538 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S568 F568 Biomuta DOID:4159 / skin cancer [ cosmic ]
S571 C571 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S683 T683 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S691 F691 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S805 L805 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K819 T819 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S880 N880 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1013 C1013 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1068 M1068 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1093 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1110 G1110 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1119 F1119 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1121 G1121 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1133 T1133 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1133 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T1136 M1136 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1164 F1164 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1186 A1186 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1192 G1192 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1248 T1248 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S1266 F1266 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K1303 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1394 Y1394 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1420 C1420 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1581 F1581 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1588 L1588 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1588 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1592 I1592 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1616 F1616 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1733 L1733 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]