iPTMnet Report for Q7Z422 (SZRD1)
Protein Information
UniProt AC / UniProt ID | Q7Z422 / SZRD1_HUMAN |
Protein Name | SUZ domain-containing protein 1 |
Gene Name | Name: SZRD1 Synonyms:C1orf144; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z422 |
PRO Name | SUZ domain-containing protein 1 (human) |
Definition | A SUZ domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hSZRD1 |
Category | organism-gene |
Q7Z422 (SZRD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 20068231, 18669648, 17081983, ... | ||
S39 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 18669648, ... | ||
S51 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 20068231 | ||
T67 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
T67 | Phosphorylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 17287340 | ||
S73 | O-Glycosylation | score1 | GlyGen | 31492838, 31373491 | ||
S73 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S74 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 17287340 | ||
S77 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T78 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S79 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
T82 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
S107 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 17081983, ... | ||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
T121 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983, 18220336 | ||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
K149 | Methylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S37 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S39 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S51 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S68 | Phosphorylation | score0 | HPRD | 18669648, 17287340, 20068231 | ||
S73 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S74 | Phosphorylation | score0 | HPRD | 18669648, 17287340, 20068231 | ||
S77 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T78 | Phosphorylation | score0 | HPRD | 18669648 | ||
S105 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S107 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 18707149, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K19 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S37 | F37 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T67 | I67 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T82 | I82 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:2998 / testicular cancer [ cosmic ] | |
S129 | N129 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |