iPTMnet Report for Q7Z418 (KCNK18)
Protein Information
UniProt AC / UniProt ID | Q7Z418 / KCNKI_HUMAN |
Protein Name | Potassium channel subfamily K member 18 |
Gene Name | Name: KCNK18 Synonyms:TRESK,TRIK; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z418 |
PRO Name | potassium channel subfamily K member 18 (human) |
Definition | A potassium channel subfamily K member 18 that is encoded in the genome of human. |
Short Label | hKCNK18 |
Category | organism-gene |
Q7Z418 (KCNK18) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N70 | N-Glycosylation | score3 | GlyGen UniProt | 20006580 | ||
T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Methylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
S252 | Phosphorylation | P17612 (PRKACA) | score3 | neXtProt PhosphoSitePlus | 18397886 | |
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
S267 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S178 | P178 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S178 | Y178 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S184 | F184 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S252 | L252 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
S264 | F264 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |