iPTMnet Report for Q7Z418 (KCNK18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z418 / KCNKI_HUMAN
Protein Name Potassium channel subfamily K member 18
Gene Name Name: KCNK18
Synonyms:TRESK,TRIK;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z418
DAG View
PRO Name potassium channel subfamily K member 18 (human)
Definition A potassium channel subfamily K member 18 that is encoded in the genome of human.
Short Label hKCNK18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z418 (KCNK18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N70 N-Glycosylation GlyGen   UniProt 20006580
T173 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K187 Methylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
S252 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 18397886
S262 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S178 P178 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S178 Y178 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S184 F184 Biomuta DOID:4159 / skin cancer [ cosmic ]
S252 L252 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S264 F264 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]