Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z309 / PBIR2_HUMAN
Protein Name PABIR family member 2
Gene Name Name: PABIR2
Synonyms:FAM122B;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z309
DAG View
PRO Name PABIR family member 2 (human)
Definition A PABIR family member 2 that is encoded in the genome of human.
Short Label hPABIR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z309 (PABIR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S15 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S25 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S33 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S36 Phosphorylation PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 20068231, ...18220336
T51 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
S55 O-Glycosylation GlyGen 30379171, 31373491
S55 Phosphorylation PhosphoSitePlus
S58 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
L63 Phosphorylation UniProt 20068231
S93 Phosphorylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
T112 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S115 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18220336, 18669648, 19690332, 20068231
S119 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18220336, 18669648, 19690332
T121 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
R122 Methylation PhosphoSitePlus   UniProt 24129315
S130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S132 O-Glycosylation GlyGen 30379171, 31373491
S132 Phosphorylation PhosphoSitePlus
S137 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S141 O-Glycosylation GlyGen 30379171, 31373491
S141 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 18669648, ...19690332, 20068231
S146 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K165 Methylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
K177 Acetylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation HPRD 20068231
S25 Phosphorylation HPRD 18669648, 20068231
S33 Phosphorylation HPRD 18669648, 20068231
S50 Phosphorylation HPRD 18212344, 18767875, 19651622, ...19415658, 20068231, 17924679
T51 Phosphorylation HPRD 20068231
S58 Phosphorylation HPRD 19651622, 18669648, 20068231
T112 Phosphorylation HPRD 18669648, 20068231
S115 Phosphorylation HPRD 19413330, 18691976, 18212344, ...16964243, 18767875, 19664994, 19651622, 18669648, 19415658, 20068231, 17924679
S119 Phosphorylation HPRD 19413330, 18691976, 18212344, ...16964243, 18767875, 19664994, 19651622, 18669648, 19415658, 20068231, 17924679
T121 Phosphorylation HPRD 18767875, 18669648, 19415658, ...20068231
S130 Phosphorylation HPRD 20068231
S137 Phosphorylation HPRD 19413330, 18669648, 20068231
S141 Phosphorylation HPRD 19413330, 18669648, 20068231
S152 Phosphorylation HPRD 20068231
S238 Phosphorylation HPRD 19413330
S246 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
K77 Sumoylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 D2 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T14 A14 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
S25 N25 Biomuta DOID:1324 / lung cancer [ cosmic ]
T46 I46 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S105 Y105 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S105 F105 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T112 A112 Biomuta DOID:1319 / brain cancer [ cosmic ]
S115 F115 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R122 T122 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
R122 S122 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S134 F134 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S141 G141 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S160 G160 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]