iPTMnet Report for Q7Z2Z2 (EFL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z2Z2 / EFL1_HUMAN
Protein Name Elongation factor-like GTPase 1
Gene Name Name: EFL1
Synonyms:EFTUD1,FAM42A;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z2Z2
DAG View
PRO Name elongation factor-like GTPase 1 (human)
Definition An elongation factor-like GTPase 1 that is encoded in the genome of human.
Short Label hEFL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z2Z2 (EFL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K278 Methylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K528 Acetylation PhosphoSitePlus   UniProt 19608861
K635 Ubiquitination PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
K804 Methylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
K901 Ubiquitination PhosphoSitePlus
T942 Phosphorylation PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
T951 Phosphorylation PhosphoSitePlus
Y954 Phosphorylation PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
T1069 Phosphorylation PhosphoSitePlus
Y1074 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T743 Phosphorylation HPRD 20068231
S752 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T692 Phosphorylation HPRD 20068231
S701 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 E14 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K701 N701 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K804 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y954 D954 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y954 C954 Biomuta DOID:363 / uterine cancer [ icgc ]
T1019 P1019 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]