Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7RTM1 / OTOP1_HUMAN
Protein Name Proton channel OTOP1
Gene Name Name: OTOP1
Organism Homo sapiens (Human)

PRO ID PR:Q7RTM1
DAG View
PRO Name proton channel OTOP1 (human)
Definition A proton channel OTOP1 that is encoded in the genome of human.
Short Label hOTOP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7RTM1 (OTOP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S382 Phosphorylation IEDB   PhosphoSitePlus 27869121
S519 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S339 Y339 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S519 T519 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S519 G519 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]