iPTMnet Report for Q7L5N7 (LPCAT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L5N7 / PCAT2_HUMAN
Protein Name Lysophosphatidylcholine acyltransferase 2
Gene Name Name: LPCAT2
Synonyms:AGPAT11,AYTL1;
Organism Homo sapiens (Human)

PRO ID PR:Q7L5N7
DAG View
PRO Name lysophosphatidylcholine acyltransferase 2 (human)
Definition A lysophosphatidylcholine acyltransferase 2 that is encoded in the genome of human.
Short Label hLPCAT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L5N7 (LPCAT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation PhosphoSitePlus
S34 Phosphorylation P49137 (MAPKAPK2) neXtProt   PhosphoSitePlus   RLIMS-P 20663880
K105 Ubiquitination PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K204 Acetylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
Y483 Phosphorylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S530 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S121 P121 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K386 N386 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S482 P482 Biomuta DOID:4159 / skin cancer [ cosmic ]
S482 F482 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y483 C483 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S539 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]