iPTMnet Report for Q7L4E1 (MIGA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L4E1 / MIGA2_HUMAN
Protein Name Mitoguardin 2
Gene Name Name: MIGA2
Synonyms:C9orf54;ORFNames:PSEC0112;
Organism Homo sapiens (Human)

PRO ID PR:Q7L4E1
DAG View
PRO Name mitoguardin 2 (human)
Definition A mitoguardin 2 that is encoded in the genome of human.
Short Label hMIGA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L4E1 (MIGA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K96 Methylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   UniProt 23186163
S228 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
T273 Phosphorylation PhosphoSitePlus   UniProt 23186163
S276 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S295 Phosphorylation UniProt 33124732
K352 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S111 I111 Biomuta DOID:3571 / liver cancer [ cosmic ]
S239 F239 Biomuta DOID:4159 / skin cancer [ cosmic ]