Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L3T8 / SYPM_HUMAN
Protein Name Probable proline--tRNA ligase, mitochondrial precursor
Gene Name Name: PARS2
Organism Homo sapiens (Human)

PRO ID PR:Q7L3T8
DAG View
PRO Name probable proline--tRNA ligase, mitochondrial (human)
Definition A probable proline--tRNA ligase, mitochondrial that is encoded in the genome of human.
Short Label hPARS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L3T8 (PARS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R55 Methylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
T163 Phosphorylation IEDB 31848261
K175 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R55 L55 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T163 M163 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]