iPTMnet Report for Q7L190 (DPPA4)
Protein Information
UniProt AC / UniProt ID | Q7L190 / DPPA4_HUMAN |
Protein Name | Developmental pluripotency-associated protein 4 |
Gene Name | Name: DPPA4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7L190 |
PRO Name | developmental pluripotency-associated protein 4 (human) |
Definition | A developmental pluripotency-associated protein 4 that is encoded in the genome of human. |
Short Label | hDPPA4 |
Category | organism-gene |
Q7L190 (DPPA4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S10 | Phosphorylation | score0 | HPRD | 17081983 | ||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
T215 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 19664994, 19664995 | ||
S221 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 19664995 | ||
S226 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K299 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S25 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S25 | L25 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K47 | N47 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S221 | F221 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K299 | Q299 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
K299 | E299 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |