iPTMnet Report for Q712K3 (UBE2R2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q712K3 / UB2R2_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 R2
Gene Name Name: UBE2R2
Synonyms:CDC34B,UBC3B;
Organism Homo sapiens (Human)

PRO ID PR:Q712K3
DAG View
PRO Name ubiquitin-conjugating enzyme E2 R2 (human)
Definition A ubiquitin-conjugating enzyme E2 R2 that is encoded in the genome of human.
Short Label hUBE2R2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q712K3 (UBE2R2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Ubiquitination PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
R166 Methylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
T186 O-Glycosylation GlyGen 28657654
Y190 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
S233 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 18669648, 12037680
S238 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K63 E63 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R166 M166 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K193 Q193 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S233 F233 Biomuta DOID:4159 / skin cancer [ cosmic ]
S238 L238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]