iPTMnet Report for Q70Z53 (FRA10AC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q70Z53 / F10C1_HUMAN
Protein Name Protein FRA10AC1
Gene Name Name: FRA10AC1
Synonyms:C10orf4;ORFNames:PRO2972;
Organism Homo sapiens (Human)

PRO ID PR:Q70Z53
DAG View
PRO Name protein FRA10AC1 (human)
Definition A protein FRA10AC1 that is encoded in the genome of human.
Short Label hFRA10AC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q70Z53 (FRA10AC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S9 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus   UniProt 23186163
K36 Acetylation PhosphoSitePlus
K36 Sumoylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K40 Acetylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K45 Acetylation PhosphoSitePlus
R58 Methylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
C175 Methylation IEDB 31844290
K178 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S251 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S252 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S257 Phosphorylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S283 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S251 Phosphorylation HPRD 18669648
S252 Phosphorylation HPRD 18669648
S278 Phosphorylation HPRD 19413330, 19651622
S283 Phosphorylation HPRD 19413330, 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y84 C84 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K92 N92 Biomuta DOID:1324 / lung cancer [ cosmic ]
K103 N103 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
C175 Y175 Biomuta DOID:4159 / skin cancer [ cosmic ]
S251 A251 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S285 L285 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]