iPTMnet Report for Q70EL2 (USP45)
Protein Information
UniProt AC / UniProt ID | Q70EL2 / UBP45_HUMAN |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 45 |
Gene Name | Name: USP45 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q70EL2 |
PRO Name | ubiquitin carboxyl-terminal hydrolase 45 (human) |
Definition | A ubiquitin carboxyl-terminal hydrolase 45 that is encoded in the genome of human. |
Short Label | hUSP45 |
Category | organism-gene |
Q70EL2 (USP45) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
K391 | Ubiquitination | score1 | PhosphoSitePlus | |||
S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
S597 | Phosphorylation | score1 | PhosphoSitePlus | |||
S599 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y666 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S432 | T432 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S474 | G474 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S597 | C597 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
Y666 | D666 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |