iPTMnet Report for Q6ZT12 (UBR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZT12 / UBR3_HUMAN
Protein Name E3 ubiquitin-protein ligase UBR3
Gene Name Name: UBR3
Synonyms:KIAA2024,ZNF650;
Organism Homo sapiens (Human)

PRO ID PR:Q6ZT12
DAG View
PRO Name E3 ubiquitin-protein ligase UBR3 (human)
Definition An E3 ubiquitin-protein ligase UBR3 that is encoded in the genome of human.
Short Label hUBR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZT12 (UBR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K36 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Y411 Phosphorylation PhosphoSitePlus
C464 Methylation IEDB 31844290
S912 Phosphorylation PhosphoSitePlus
Y913 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
K1012 Ubiquitination PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus
K1045 Ubiquitination PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus
K1064 Ubiquitination PhosphoSitePlus
T1080 Phosphorylation PhosphoSitePlus
K1141 Methylation PhosphoSitePlus
K1141 Ubiquitination PhosphoSitePlus
K1159 Ubiquitination PhosphoSitePlus
T1161 Phosphorylation PhosphoSitePlus
K1168 Acetylation PhosphoSitePlus
K1174 Acetylation PhosphoSitePlus
K1174 Ubiquitination PhosphoSitePlus
S1199 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
K1274 Ubiquitination PhosphoSitePlus
Y1284 Phosphorylation PhosphoSitePlus
K1355 Ubiquitination PhosphoSitePlus
K1390 Ubiquitination PhosphoSitePlus
K1397 Ubiquitination PhosphoSitePlus
K1424 Methylation PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
K1480 Ubiquitination PhosphoSitePlus
T1565 Phosphorylation PhosphoSitePlus
K1588 Ubiquitination PhosphoSitePlus
K1733 Ubiquitination PhosphoSitePlus
K1771 Ubiquitination PhosphoSitePlus
K1853 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K1168 E1168 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K1174 N1174 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1397 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1565 I1565 Biomuta DOID:4159 / skin cancer [ cosmic ]