iPTMnet Report for Q6UXY8 (TMC5)
Protein Information
UniProt AC / UniProt ID | Q6UXY8 / TMC5_HUMAN |
Protein Name | Transmembrane channel-like protein 5 |
Gene Name | Name: TMC5 ORFNames:UNQ8238/PRO33604; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6UXY8 |
PRO Name | transmembrane channel-like protein 5 (human) |
Definition | A transmembrane channel-like protein 5 that is encoded in the genome of human. |
Short Label | hTMC5 |
Category | organism-gene |
Q6UXY8 (TMC5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y16 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y19 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y29 | Phosphorylation | score1 | PhosphoSitePlus | |||
K31 | Methylation | score1 | PhosphoSitePlus | |||
Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y47 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y55 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y65 | Phosphorylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y83 | Phosphorylation | score1 | PhosphoSitePlus | |||
S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y91 | Phosphorylation | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y118 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y146 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
S266 | Phosphorylation | score1 | PhosphoSitePlus | |||
S269 | Phosphorylation | score1 | PhosphoSitePlus | |||
S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
T361 | Phosphorylation | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
K583 | Acetylation | score1 | PhosphoSitePlus | |||
Y782 | Phosphorylation | score1 | PhosphoSitePlus | |||
T785 | Phosphorylation | score1 | PhosphoSitePlus | |||
K956 | Ubiquitination | score1 | PhosphoSitePlus | |||
K963 | Ubiquitination | score1 | PhosphoSitePlus | |||
S967 | Phosphorylation | score1 | PhosphoSitePlus | |||
S968 | Phosphorylation | score1 | PhosphoSitePlus | |||
S990 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S48 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S48 | T48 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y55 | C55 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
Y65 | C65 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y65 | N65 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S77 | Y77 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S84 | F84 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S84 | A84 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S95 | C95 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S168 | R168 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S266 | N266 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S270 | L270 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K963 | N963 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S967 | T967 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
S968 | L968 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |