iPTMnet Report for Q6UW60 (PCSK4)
Protein Information
UniProt AC / UniProt ID | Q6UW60 / PCSK4_HUMAN |
Protein Name | Proprotein convertase subtilisin/kexin type 4 precursor |
Gene Name | Name: PCSK4 Synonyms:PC4;ORFNames:UNQ2757/PRO6496; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6UW60 |
PRO Name | proprotein convertase subtilisin/kexin type 4 (human) |
Definition | A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of human. |
Short Label | hPCSK4 |
Category | organism-gene |
Q6UW60 (PCSK4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
T635 | Phosphorylation | score1 | PhosphoSitePlus | |||
T641 | Phosphorylation | score1 | PhosphoSitePlus | |||
S650 | Phosphorylation | score1 | PhosphoSitePlus | |||
S651 | Phosphorylation | score1 | PhosphoSitePlus | |||
S655 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S258 | C258 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S655 | F655 | Biomuta | DOID:4159 / skin cancer [ icgc ] |