iPTMnet Report for Q6UVK1 (CSPG4)
Protein Information
UniProt AC / UniProt ID | Q6UVK1 / CSPG4_HUMAN |
Protein Name | Chondroitin sulfate proteoglycan 4 precursor |
Gene Name | Name: CSPG4 Synonyms:MCSP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6UVK1 |
PRO Name | chondroitin sulfate proteoglycan 4 (human) |
Definition | A chondroitin sulfate proteoglycan 4 that is encoded in the genome of human. |
Short Label | hCSPG4 |
Category | organism-gene |
Q6UVK1 (CSPG4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
S643 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y743 | Phosphorylation | score1 | PhosphoSitePlus | |||
S995 | O-Glycosylation | score2 | GlyGen UniProt | 36213313, 32337544 | ||
N1449 | N-Glycosylation | score1 | GlyGen | 29671580 | ||
T1591 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2036 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2042 | Phosphorylation | score1 | PhosphoSitePlus | |||
N2075 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
T2077 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2079 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2203 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S2204 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T2252 | Phosphorylation | P17252 (PRKCA) | score3 | neXtProt Signor | 15504744 | |
T2261 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2263 | Ubiquitination | score1 | PhosphoSitePlus | |||
T2274 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2277 | Ubiquitination | score1 | PhosphoSitePlus | |||
T2310 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2316 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y2320 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T2252 | M2252 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
T2274 | P2274 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K2277 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |