iPTMnet Report for Q6UUV7 (CRTC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UUV7 / CRTC3_HUMAN
Protein Name CREB-regulated transcription coactivator 3
Gene Name Name: CRTC3
Synonyms:TORC3;
Organism Homo sapiens (Human)

PRO ID PR:Q6UUV7
DAG View
PRO Name CREB-regulated transcription coactivator 3 (human)
Definition A CREB-regulated transcription coactivator 3 that is encoded in the genome of human.
Short Label hCRTC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UUV7 (CRTC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163
K14 Sumoylation PhosphoSitePlus
K18 Sumoylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
S62 Phosphorylation P57059 (SIK1) neXtProt   PhosphoSitePlus   UniProt 23033494, 23186163, 20068231
S67 Phosphorylation PhosphoSitePlus
S71 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
R87 Methylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K147 Sumoylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
S162 Phosphorylation P57059 (SIK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 23033494, 25351958, 16817901
K174 Sumoylation PhosphoSitePlus
K213 Sumoylation PhosphoSitePlus
K222 Sumoylation PhosphoSitePlus
K226 Sumoylation PhosphoSitePlus
K232 Sumoylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S273 Phosphorylation UniProt 30611118
S305 Phosphorylation PhosphoSitePlus
S320 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S321 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S321 Phosphorylation PhosphoSitePlus
S326 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S327 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S327 Phosphorylation PhosphoSitePlus
S329 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S329 Phosphorylation P57059 (SIK1) neXtProt   PhosphoSitePlus   UniProt 23033494, 23186163, 19690332
S332 Phosphorylation PhosphoSitePlus   UniProt 23186163
T340 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S343 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S344 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S344 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
T352 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
T352 Phosphorylation PhosphoSitePlus
S353 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S353 Phosphorylation PhosphoSitePlus
S363 O-Glycosylation GlyGen 34846842, 33214551, 31492838, ...29351928, 35132862, 35289036, 35254053, 29237092, 30059200
S363 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S370 Phosphorylation P57059 (SIK1) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 23033494, 25351958, 23186163, ...19690332
S373 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 18669648, 30611118, 23186163
T394 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 30611118, 23186163
S406 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus   UniProt 23186163
S411 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 18220336
Y448 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18691976
S62 Phosphorylation HPRD 18669648, 20068231
S329 Phosphorylation HPRD 20068231
S391 Phosphorylation HPRD 18669648, 17081983, 20068231
T394 Phosphorylation HPRD 17081983, 20068231
S396 Phosphorylation HPRD 18669648, 17081983, 20068231
S410 Phosphorylation HPRD 20068231
S411 Phosphorylation HPRD 20068231
S443 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18691976
S62 Phosphorylation HPRD 18669648, 20068231
S329 Phosphorylation HPRD 20068231
S391 Phosphorylation HPRD 18669648, 17081983, 20068231
T394 Phosphorylation HPRD 17081983, 20068231
S396 Phosphorylation HPRD 18669648, 17081983, 20068231
S410 Phosphorylation HPRD 20068231
S411 Phosphorylation HPRD 20068231
S443 Phosphorylation HPRD 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q6UUV7 (CRTC3) S391 Q15257 (PTPA) increased_association eFIP 30611118
Phosphorylation Q96PU5 (NEDD4L) S448 Q6UUV7 (CRTC3) unknown eFIP 29505301