iPTMnet Report for Q6PJT7 (ZC3H14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PJT7 / ZC3HE_HUMAN
Protein Name Zinc finger CCCH domain-containing protein 14
Gene Name Name: ZC3H14
Organism Homo sapiens (Human)

PRO ID PR:Q6PJT7
DAG View
PRO Name zinc finger CCCH domain-containing protein 14 (human)
Definition A zinc finger CCCH domain-containing protein 14 that is encoded in the genome of human.
Short Label hZC3H14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PJT7 (ZC3H14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T5 Phosphorylation PhosphoSitePlus
S75 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T77 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T78 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T78 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K99 Sumoylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S132 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S132 Phosphorylation PhosphoSitePlus
T133 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T133 Phosphorylation PhosphoSitePlus
S134 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S135 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
K139 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K175 Sumoylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K198 Sumoylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
T202 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T204 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T204 Phosphorylation PhosphoSitePlus
S211 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S211 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
S220 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S225 Phosphorylation PhosphoSitePlus
S240 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S240 Phosphorylation PhosphoSitePlus   UniProt 23186163
K245 Ubiquitination PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus   UniProt 23186163
K283 Sumoylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K307 Acetylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
T325 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T325 Phosphorylation PhosphoSitePlus
S327 O-Glycosylation GlyGen 34846842
S327 Phosphorylation PhosphoSitePlus   UniProt 23186163
S329 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S331 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
K337 Ubiquitination PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S347 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K352 Sumoylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K357 Acetylation PhosphoSitePlus   UniProt 19608861
K357 Sumoylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S360 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S365 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S365 Phosphorylation PhosphoSitePlus
T367 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T367 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
T369 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T369 Phosphorylation PhosphoSitePlus
T370 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
Y372 Phosphorylation PhosphoSitePlus
S373 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S373 Phosphorylation PhosphoSitePlus
T374 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
K378 Ubiquitination PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
T387 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T387 Phosphorylation PhosphoSitePlus
T389 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T389 Phosphorylation PhosphoSitePlus
S390 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S390 Phosphorylation PhosphoSitePlus   UniProt 23186163
S403 Phosphorylation PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus   UniProt 23186163
K413 Sumoylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus   UniProt 23186163
K424 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
Y454 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K473 Sumoylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
K489 Methylation PhosphoSitePlus
K489 Sumoylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus   UniProt 23186163
K512 Ubiquitination PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 24275569, 19690332, 20068231
S527 Phosphorylation PhosphoSitePlus
Y531 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus   UniProt 17081983
K623 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
K633 Sumoylation PhosphoSitePlus
T655 O-Glycosylation GlyGen 33465208
S658 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S665 Phosphorylation PhosphoSitePlus
K689 Acetylation PhosphoSitePlus
K690 Sumoylation PhosphoSitePlus
K728 Acetylation PhosphoSitePlus
K728 Sumoylation PhosphoSitePlus
T734 O-Glycosylation GlyGen 32574038
T734 Phosphorylation PhosphoSitePlus
S735 O-Glycosylation GlyGen 23301498, 29249144, 35138101, ...30620550, 31492838, 35289036, 29351928, 33465208, 29237092, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S735 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S365 Phosphorylation HPRD 20068231
T367 Phosphorylation HPRD 20068231
S373 Phosphorylation HPRD 19413330
T380 Phosphorylation HPRD 20068231
S390 Phosphorylation HPRD 18077418, 18452278
S409 Phosphorylation HPRD 18452278, 20068231, 18707149
T417 Phosphorylation HPRD 20068231
S450 Phosphorylation HPRD 17525332, 18077418
S498 Phosphorylation HPRD 20068231
S515 Phosphorylation HPRD 18691976, 17081983, 18212344, ...20058876, 19664995, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231, 19691289
Y531 Phosphorylation HPRD 20068231
S533 Phosphorylation HPRD 20068231, 18452278
T550 Phosphorylation HPRD 20068231
S553 Phosphorylation HPRD 20068231
S620 Phosphorylation HPRD 17081983, 20068231, 18212344
S665 Phosphorylation HPRD 20068231
S735 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S665 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S365 Phosphorylation HPRD 20068231
T367 Phosphorylation HPRD 20068231
S373 Phosphorylation HPRD 19413330
T380 Phosphorylation HPRD 20068231
S390 Phosphorylation HPRD 18077418, 18452278
S409 Phosphorylation HPRD 18452278, 20068231, 18707149
T417 Phosphorylation HPRD 20068231
S421 Phosphorylation PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
S464 Phosphorylation HPRD 17081983, 20068231, 18212344
S509 Phosphorylation HPRD   PhosphoSitePlus 20068231
S578 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S331 Phosphorylation HPRD 20068231
T333 Phosphorylation HPRD 20068231
S339 Phosphorylation HPRD 19413330
T346 Phosphorylation HPRD 20068231
S356 Phosphorylation HPRD 18077418, 18452278
T371 Phosphorylation PhosphoSitePlus
S375 Phosphorylation HPRD 18452278, 20068231, 18707149
T383 Phosphorylation HPRD 20068231
K428 Ubiquitination PhosphoSitePlus
S455 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231, 18212344
S500 Phosphorylation HPRD 20068231
S570 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S421 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S191 Phosphorylation HPRD 17081983, 20068231, 18212344
S236 Phosphorylation HPRD   PhosphoSitePlus 20068231
S305 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K588 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S75 C75 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T78 S78 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K99 N99 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S129 C129 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S132 F132 Biomuta DOID:4159 / skin cancer [ cosmic ]
S135 L135 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T146 A146 Biomuta DOID:3571 / liver cancer [ cosmic ]
S195 Y195 Biomuta DOID:363 / uterine cancer [ icgc ]
K197 R197 Biomuta DOID:363 / uterine cancer [ cosmic ]
T204 I204 Biomuta DOID:4159 / skin cancer [ cosmic ]
S220 N220 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S240 N240 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y321 F321 Biomuta DOID:4159 / skin cancer [ cosmic ]
S323 F323 Biomuta DOID:363 / uterine cancer [ icgc ]
K352 N352 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S360 A360 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T370 A370 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T374 S374 Biomuta DOID:3571 / liver cancer [ cosmic ]
S375 G375 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K378 Q378 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T383 K383 Biomuta DOID:4159 / skin cancer [ cosmic ]
S409 G409 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T417 K417 Biomuta DOID:4159 / skin cancer [ cosmic ]
K418 Q418 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y454 C454 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S515 N515 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S553 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]