iPTMnet Report for Q6PJG2 (MIDEAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PJG2 / MDEAS_HUMAN
Protein Name Mitotic deacetylase-associated SANT domain protein
Gene Name Name: MIDEAS
Synonyms:C14orf117;
Organism Homo sapiens (Human)

PRO ID PR:Q6PJG2
DAG View
PRO Name mitotic deacetylase-associated SANT domain protein (human)
Definition A protein that is a translation product of the MIDEAS gene in human.
Short Label hMIDEAS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PJG2 (MIDEAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
K8 Sumoylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K42 Sumoylation PhosphoSitePlus
S57 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
T58 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
S59 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
S69 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
T83 O-Glycosylation GlyGen 23301498, 33214551, 35254053, ...32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29351928, 28657654, 29237092
S117 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
S132 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
T133 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
S148 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
K166 Sumoylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
R177 Methylation PhosphoSitePlus
R180 Methylation IEDB   PhosphoSitePlus 27503676
K186 Methylation PhosphoSitePlus
R193 Methylation PhosphoSitePlus   UniProt 24129315
S200 Phosphorylation PhosphoSitePlus
K206 Sumoylation PhosphoSitePlus
R227 Methylation PhosphoSitePlus
R231 Methylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S438 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29351928, 28657654, 29237092
S438 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
R447 Methylation PhosphoSitePlus   UniProt 24129315
T454 Phosphorylation PhosphoSitePlus
R455 Methylation PhosphoSitePlus
S461 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18452278, 19651622, 18669648, 19690332, 20068231
T468 Phosphorylation HPRD   PhosphoSitePlus 17081983
K483 Ubiquitination PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
T513 Phosphorylation PhosphoSitePlus
K514 Acetylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S530 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...32574038, 30059200, 29351928, 35132862, 31492838, 35254053, 28657654, 29237092
K562 Sumoylation PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
K590 Sumoylation PhosphoSitePlus
Y624 Phosphorylation HPRD   PhosphoSitePlus 20068231
S625 Phosphorylation HPRD   PhosphoSitePlus 17081983
T628 Phosphorylation PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
Y654 Phosphorylation PhosphoSitePlus
T655 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19690332, 18452278
S661 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18220336, 19690332, 18452278
T687 Phosphorylation PhosphoSitePlus
T694 Phosphorylation PhosphoSitePlus
T698 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231, ...18452278
S700 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18452278
T704 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18452278, 19651622, 18669648, ...24275569, 19690332, 20068231
S709 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19690332, 18452278
T715 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18452278, 19651622, 18669648, ...24275569, 19690332
K748 Ubiquitination PhosphoSitePlus
K843 Sumoylation PhosphoSitePlus
K843 Ubiquitination PhosphoSitePlus
T893 Phosphorylation HPRD   PhosphoSitePlus 18452278
S894 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S923 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S925 Phosphorylation PhosphoSitePlus
K969 Acetylation PhosphoSitePlus
S979 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
S996 Phosphorylation HPRD   PhosphoSitePlus 19651622
K1004 Acetylation PhosphoSitePlus
K1004 Ubiquitination PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S132 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
Y158 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R177 H177 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R180 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S200 Y200 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R227 W227 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R227 Q227 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R231 W231 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R447 L447 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R447 W447 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R447 Q447 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T454 M454 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R455 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R455 P455 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
R455 Q455 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S625 C625 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S632 I632 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y654 C654 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S661 C661 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T687 M687 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T704 P704 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K748 T748 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T893 M893 Biomuta DOID:1319 / brain cancer [ icgc ]
S925 G925 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S979 L979 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S991 P991 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S991 A991 Biomuta DOID:3571 / liver cancer [ cosmic ]