Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PIU2 / NCEH1_HUMAN
Protein Name Neutral cholesterol ester hydrolase 1
Gene Name Name: NCEH1
Synonyms:AADACL1,KIAA1363;
Organism Homo sapiens (Human)

PRO ID PR:Q6PIU2
DAG View
PRO Name neutral cholesterol ester hydrolase 1 (human)
Definition A neutral cholesterol ester hydrolase 1 that is encoded in the genome of human.
Short Label hNCEH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PIU2 (NCEH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T85 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus
N270 N-Glycosylation GlyGen 29741879, 19592704
N287 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
T289 O-Glycosylation GlyGen 33214551, 34725712, 34019948, ...35254053
S295 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
N389 N-Glycosylation GlyGen 19592704


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T85 R85 Biomuta DOID:1324 / lung cancer [ icgc ]
S144 F144 Biomuta DOID:1115 / sarcoma [ icgc ]
T240 N240 Biomuta DOID:363 / uterine cancer [ icgc ]