iPTMnet Report for Q6PGQ7 (BORA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6PGQ7 / BORA_HUMAN
Protein Name Protein aurora borealis
Gene Name Name: BORA
Synonyms:C13orf34;
Organism Homo sapiens (Human)

PRO ID PR:Q6PGQ7
DAG View
PRO Name protein aurora borealis (human)
Definition A protein aurora borealis that is encoded in the genome of human.
Short Label hBORA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6PGQ7 (BORA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y31 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S41 Phosphorylation IEDB   PhosphoSitePlus 32387766
K46 Ubiquitination PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus   RLIMS-P 24675888
Y82 Phosphorylation PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   RLIMS-P 33771996
K120 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
C154 Methylation IEDB 31844290
S183 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S188 Phosphorylation PhosphoSitePlus   RLIMS-P 25742493
S189 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S190 Phosphorylation phospho.ELM 18669648
S191 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S239 Phosphorylation PhosphoSitePlus
S252 Phosphorylation neXtProt   PRO   PhosphoSitePlus   RLIMS-P 25742493, 18521620
S252 Phosphorylation P06493 (CDK1) PhosphoSitePlus 18521620
S270 Phosphorylation PhosphoSitePlus   UniProt 19690332
S274 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 23442801
S274 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 23442801
S278 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 23442801
S278 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 23442801
T296 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus   RLIMS-P 25742493
S325 Phosphorylation P50750 (CDK9) PhosphoSitePlus 25742493
S331 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus
T445 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
S497 Phosphorylation neXtProt   PRO   PhosphoSitePlus   Signor 18521620, 18378770
S497 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   Signor 18521620, 18378770
T501 Phosphorylation neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor 23592782, 18521620, 18378770
T501 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   Signor 18521620, 18378770
T501 Phosphorylation Q13535 (ATR) PhosphoSitePlus 23592782
K531 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046499 (hBORA/Phos:2) pS252 PRO
PR:000046500 (hBORA/Phos:3) pS252,pS497,pT501 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P53350 (PLK1) T210 Q6PGQ7 (BORA) unknown eFIP 27721411
Phosphorylation Q6PGQ7 (BORA) S325 Q14676 (MDC1) unknown eFIP 25742493


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K120 N120 Biomuta DOID:10534 / stomach cancer [ icgc ]
S252 N252 Biomuta DOID:1781 / thyroid cancer [ icgc ]
S270 L270 Biomuta DOID:1324 / lung cancer [ cosmic ]
S270 T270 Biomuta DOID:1324 / lung cancer [ cosmic ]