iPTMnet Report for Q6P9G4 (TMEM154)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P9G4 / TM154_HUMAN
Protein Name Transmembrane protein 154 precursor
Gene Name Name: TMEM154
Organism Homo sapiens (Human)

PRO ID PR:Q6P9G4
DAG View
PRO Name transmembrane protein 154 (human)
Definition A transmembrane protein 154 that is encoded in the genome of human.
Short Label hTMEM154
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P9G4 (TMEM154) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T53 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T57 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S111 Phosphorylation HPRD   PhosphoSitePlus 18077418
S112 Phosphorylation HPRD   PhosphoSitePlus 18077418
S115 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 S53 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T121 I121 Biomuta DOID:1324 / lung cancer [ cosmic ]
S140 F140 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S179 R179 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S179 G179 Biomuta DOID:10534 / stomach cancer [ cosmic ]