iPTMnet Report for Q6P3R8 (NEK5)
Protein Information
UniProt AC / UniProt ID | Q6P3R8 / NEK5_HUMAN |
Protein Name | Serine/threonine-protein kinase Nek5 |
Gene Name | Name: NEK5 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6P3R8 |
PRO Name | serine/threonine-protein kinase Nek5 (human) |
Definition | A serine/threonine-protein kinase Nek5 that is encoded in the genome of human. |
Short Label | hNEK5 |
Category | organism-gene |
Q6P3R8 (NEK5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y477 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17287340 | ||
K556 | Acetylation | score1 | PhosphoSitePlus | |||
S566 | O-Glycosylation | score1 | GlyGen | 30379171 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y477 | C477 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S566 | R566 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |